This COTTLE_readme20240528.txt file was generated on 20240528 by Brian Cottle ------------------- GENERAL INFORMATION ------------------- 1. Title of Dataset Intraoperative Characterization of Cardiac Tissue: The Potential of Light Scattering Spectroscopy 2. Author Information Principal Investigator Contact Information Name: Brian Cottle Institution: University of Utah Address: Sorenson Molecular Biotechnology Building, Room 409 36 S Wasatch Drive Salt Lake City, UT 84112 Email: brian.k.cottle@icloud.com ORCID: 0000-0002-4226-5969 Associate or Co-investigator Contact Information Name: Frank Sachse Institution: University of Utah Address: The Nora Eccles Harrison CVRTI 95 S 2000 E, Room 204A Salt Lake City, UT 84112-5000 Email: frank.sachse@utah.edu ORCID: 0000-0003-4987-705X Associate or Co-investigator Contact Information Name: Robert Hitchcock Institution: University of Utah Address: Sorenson Molecular Biotechnology Building, Room 409 36 S Wasatch Drive Salt Lake City, UT 84112 Email: r.hitchcock@utah.edu 3. Date of data collection (single date, range, approximate date) 2021-04-01 to 2023-08-31 4. Geographic location of data collection (where was data collected?): Salt Lake City, Utah 5. Information about funding sources that supported the collection of the data: These data were generated with help funding sources: NIH-R01 HL135077 NSF-GRFP 2139322 -------------------------- SHARING/ACCESS INFORMATION -------------------------- 1. Licenses/restrictions placed on the data: CC BY NC - Allows others to use and share your data non-commercially and with attribution. 2. Links to publications that cite or use the data: Cottle, Brian, et al. "Intraoperative characterization of cardiac tissue: the potential of light scattering spectroscopy." Journal of Biomedical Optics 29.6 (2024): 066005. https://doi.org/10.1117/1.jbo.29.6.066005. 3. Links to other publicly accessible locations of the data: N/A 4. Links/relationships to ancillary data sets: N/A 5. Was data derived from another source? No 6. Recommended citation for the data: Cottle, B., Sachse, F., Hitchcock, R. 2024. Intraoperative characterization of cardiac tissue: the potential of light scattering spectroscopy, The Hive: University of Utah Research Data Repository. https://doi.org/10.7278/S5d-1mxa-ffa0. --------------------- DATA & FILE OVERVIEW --------------------- This dataset contains a large number of files that follow a predictable and hierarchical ordering. 1. File List A. Filename: callibration_wavelengths.csv Short description: This .csv contains the wavelength values associated with every spectral recording in the dataset, with 3000 entries spanning wavelengths from 500nm to 1000nm in the visible light spectrum. Within the root folder of the dataset, there are 19 sub-folders, each with a name consisting of a heart-id followed by an underscore and a sample-id. For example: - 01_02 - 05_01 - 15_02 The heart-id is a unique identifier arbitrarily given to each heart as they arrived from our provider. Some heart-id numbers were skipped because those samples did not contain the correct amount or region of tissue for use in our study. Hence, the samples included here were the only ones that had sufficient tissue in the correct regions for inclusion in the study. The sample-id indicates whether the tissue sample was from the sinus or AV nodal regions in the heart. Sinus = "01", and AV = "02", since the sinus node comes first in the electrical progression of the heart. Each sample folder contains the following files/folder: - **_**_calibration_data.csv - This file contains the calibration spectral measurements used in the study associated with the given tissue sample. - {DATE}_FullFile_*.csv - Each sample folder contains several files titled "FullFile", which contain the recordings associated with the given sample, acquired across the surface of the tissue sample. To facilitate file size and processing, these are spread across the numerous "FullFile" .csv files for each dataset. The first three column entries in this file correspond to the X, Y, and Z position of the sample. - Fiduciary (Folder) - This folder contains 18 spectral recordings following the same file structure as the "FullFile" samples. Each of the .csv files contains spectral data, however those data were not used in the analysis. The information of interest associated with these files is contained in the file name, which follows a "Date Time X-Y-Z_**" format. 2. Relationship between files: Described above. 3. Additional related data collected that was not included in the current data package: N/A 4. Are there multiple versions of the dataset? No -------------------------- METHODOLOGICAL INFORMATION -------------------------- 1. Description of methods used for collection/generation of data: Tissue samples (roughly 1cm^3 in size) were gathered that included the sinus and AV nodal regions from donor pediatric human hearts. These tissue samples were then pinned to a well plate, and imaged using a custom LSS probe and micro manipulator setup to systematically sample the surface in a grid-like pattern. A full description of the data analysis and acquisition approaches can be found in the publication [Intraoperative characterization of cardiac tissue: the potential of light scattering spectroscopy." Journal of Biomedical Optics 29.6 (2024): 066005-066005]. 2. Methods for processing the data: N/A 3. Instrument- or software-specific information needed to interpret the data: N/A 4. Standards and calibration information, if appropriate: N/A 5. Environmental/experimental conditions: N/A 6. Describe any quality-assurance procedures performed on the data: N/A 7. People involved with sample collection, processing, analysis and/or submission: Sarthak Tiwari