Atypical atrial flutter is seen post-ablation in patients, and it can be challenging to map. These flutters are typically set up around areas of scar in the left atrium. MRI can reliably identify left atrial scar. We propose a personalized computational model using patient specific scar information, to generate a monodomain model. In the model conductivities are adjusted for different tissue regions and flutter was induced with a premature pacing protocol. The model was tested prospectively in patients undergoing atypical flutter ablation. The simulation-predicted flutters were visualized and presented to clinicians. Validation of the computational model was motivated by recording from electroanatomical mapping. These personalized models successfully predicted clinically observed atypical flutter circuits and at times even better than invasive maps leading to flutter termination at isthmus sites predicted by the model.

Last modified

• 10/29/2024

Creator

• Lange, Matthias
• Dosdall, Derek J.
• Kwan, Eugene
• MacLeod, Rob S.
• Bunch, T. Jared
• Ranjan, Ravi

Subject

• Biomedical Engineering

Language

• English

Identifier

• https://doi.org/10.7278/S50d-fdna-tekm

Keyword

• Biomedical Engineering
• Computer Simulation
• Atrial Flutter

Date created

• 2020-01-01 to 2022-12-31

Location

• Salt Lake City, Utah, United States

Related url

•  https://www.frontiersin.org/articles/10.3389/fcvm.2022.893752/full

Resource type

• Dataset

Source

• MeSH

License

• CC BY – Allows others to use and share your data, even commercially, with attribution.