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- Description:
- Localization of the components of the cardiac conduction system (CCS) is essential for many therapeutic procedures in cardiac surgery and interventional cardiology. While histological studies provided fundamental insights into CCS localization, this information is incomplete and difficult to translate to aid in intraprocedural localization. To advance our understanding of CCS localization, we set out to establish a framework for quantifying nodal region morphology. Using this framework, we quantitatively analyzed the sinoatrial node (SAN) and atrioventricular node (AVN) in ovine with menstrual age ranging from 4.4 to 58.3 months. In particular, we studied the SAN and AVN in relation to the epicardial and endocardial surfaces, respectively. Using anatomical landmarks, we excised the nodes and adjacent tissues, sectioned those at a thickness of 4 µm at 100 µm intervals, and applied Masson’s trichrome stain to the sections. These sections were then imaged, segmented to identify nodal tissue, and analyzed to quantify nodal depth and superficial tissue composition. The minimal SAN depth ranged between 20 and 926 µm. AVN minimal depth ranged between 59 and 1192 µm in the AVN extension region, 49 and 980 µm for the compact node, and 148 and 888 µm for the transition to His Bundle region. Using a logarithmic regression model, we found that minimal depth increased logarithmically with age for the AVN (R2=0.818, P=0.002). Also, the myocardial overlay of the AVN was heterogeneous within different regions and decreased with increasing age. Age associated alterations of SAN minimal depth were insignificant. Our study presents examples of characteristic tissue patterns superficial to the AVN and within the SAN. We suggest that the presented framework provides quantitative information for CCS localization. Our studies indicate that procedural methods and localization approaches in regions near the AVN should account for the age of patients in cardiac surgery and interventional cardiology.
- Subject:
- cardiology and physiology
- Creator:
- Frank Sachse, Brian K. Cottle, and Jordan Johnson
- Owner:
- Frank Sachse
- Language:
- English
- Date Uploaded:
- 11/13/2019
- Date Modified:
- 05/17/2023
- Date Created:
- 2018
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/doi:10.7278/S50D-546S-4RVW
-
- Description:
- Classification of barrier island morphology stems from the seminal work of M. O. Hayes and others, which linked island shape to tidal range and wave height and defined coastal energy regimes (i.e., wave-dominated, mixed energy, tide-dominated). If true, this general relationship represents a process-based framework to link modern and ancient systems, and is key for determining paleomorphodynamic relationships. Here we present a new semi-global database of barrier islands and spits (n = 702). Shape parameters (aspect, circularity, and roundness) are used to quantify island boundary shape, and assess potential correlation with coastal energy regime using global wave and tide models. In adopting the original energy classification as originally put forth (i.e., wave dominated, wave-influenced mixed, tide-influenced mixed, tide dominated), results show that wave-dominated islands have statistically different mean shape values from those in the mixed energy fields, but the two mixed energy designations are not distinct from each other. Furthermore, each energy regime field contains a wide range of island shapes, with no clear trends present. Linear regression modeling shows that tidal range and wave height account for < 10% of the documented variance in island shape, a strong indication that other controls must be considered. Therefore, while energy regime distinctions can be used descriptively, their utility in predicting and constraining island shape is limited: barrier island shape is not indicative of coastal energy regime, and vice versa. Our analysis also demonstrates empirical scaling relationships among modern barrier islands for the first time, with implications for subsurface prediction. and This is the dataset of the Modern Barrier Island Database published in Mulhern et al., 2017 Marine Geology paper titled "Is Barrier Island Morphology a Function of Wave and Tide Regime?" with the DOI https://doi.org/10.1016/j.margeo.2017.02.016. If using this dataset please cite both the dataset and the paper.
- Keyword:
- paleomorphodynamic relationships, geology, barrier island, shallow marine, island shape, wave-dominated islands, shoreline morphology, Modern Barrier Island Database, and coastal geomorphology
- Subject:
- Geology
- Creator:
- Johnson, Cari L., Mulhern, Julia S., and Martin, John M.
- Owner:
- Julia Mulhern
- Language:
- English
- Date Uploaded:
- 09/08/2021
- Date Modified:
- 06/03/2024
- Date Created:
- 2015-01-01 to 2017-12-31
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50d-5pzj-r9vr
-
- Description:
- While several studies have qualitatively investigated age- and region-dependent adhesion between the vitreous and retina, no studies have directly measured the vitreoretinal strength of adhesion. In this study, we developed a rotational peel device and associated methodology to measure the maximum and steady-state peel forces between the vitreous and the retina. Vitreoretinal adhesion in the equator and posterior pole were measured in human eyes from donors ranging 30 to 79 years of age, and in sheep eyes from premature, neonatal, young lamb, and young adult sheep. In human eyes, maximum peel force in the equator (7.24 ± 4.13 mN) was greater than in the posterior pole (4.08 ± 2.03 mN). This trend was especially evident for younger eyes from donors 30 to 39 years of age. After 60 years of age, there was a significant decrease in the maximum equatorial (4.69 ± 2.52 mN, p = 0.016) and posterior pole adhesion (2.95 ± 1.25 mN, p = 0.037). In immature sheep eyes, maximum adhesion was 7.60 ± 3.06 mN, and did not significantly differ between the equator and posterior pole until young adulthood. At this age, the maximum adhesion in the equator nearly doubled (16.67 ± 7.45 mN) that of the posterior pole, similar to the young adult human eyes. Light microscopy images suggest more disruption of the inner limiting membrane (ILM) in immature sheep eyes compared to adult sheep eyes. Interestingly, in human eyes, ILM disruption was significantly greater in the posterior pole (p < 0.05) and in people over 60 years of age (p < 0.02). These findings supplement the current discussion surrounding age-related posterior vitreous detachment, and the risk factors and physiological progressions associated with this condition. In addition, these data further our understanding of the biomechanical mechanisms of vitreoretinal adhesion, and can be used to develop age- appropriate computational models simulating retinal detachment, hemorrhaging, or retinal trauma. See Creveling CJ, Colter J, Coats B. 2018. Changes in vitreoretinal adhesion with age and region in human and sheep eyes. Frontiers in Bioengineering and Biotechnology 6. https://doi.org/10.3389/fbioe.2018.00153.
- Keyword:
- ophthalmology, retina, vitreous, adhesion, ocular, human, eye, peel test, and sheep
- Subject:
- Quantitative measurement and Vitreoretinal adhesion
- Creator:
- Coats, Brittany and Creveling, Christopher
- Contributor:
- Colter, Jourdan
- Owner:
- BRIAN MCBRIDE
- Based Near Label Tesim:
- Salt Lake City, Utah, United States
- Language:
- English
- Date Uploaded:
- 07/10/2019
- Date Modified:
- 06/03/2024
- Date Created:
- Completed 2017-06-01
- License:
- CC BY – Allows others to use and share your data, even commercially, with attribution.
- Resource Type:
- Image, Dataset, and Video
- Identifier:
- https://doi.org/10.7278/S5BK19H3
-
- Description:
- This dataset is a custom Kraken2 formatted database for the identification of Fungi from shotgun metagenomic data. Kraken2 is a k-mer based read classifier (Wood et al. 2019; https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1891-0). The dataset was built with the default k-mer length (k=35) from all publicly available fungal genomes at JGI Mycocosm ( https://mycocosm.jgi.doe.gov/mycocosm/home), and all archaea, bacteria, viral, plasmid, human, fungi, plant, and protozoa genomes, as well as the UniVec Core and nt reference database at NCBI ( https://www.ncbi.nlm.nih.gov/). The reference genomes and sequences were downloaded from JGI and NCBI in March 2020.
- Keyword:
- protozoa, Kraken2 database, plant, bacteria, genomes, fungi, human, archaea, plasmid, and virus
- Subject:
- Mycology and Genomics
- Creator:
- Dentinger, Bryn T. M.
- Owner:
- Bryn Dentinger
- Language:
- English
- Date Uploaded:
- 06/08/2022
- Date Modified:
- 06/03/2024
- Date Created:
- 2020-03-29
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Software or Program Code and Dataset
- Identifier:
- https://doi.org/10.7278/S50d-154b-fppf
-
- Description:
- : Forests play a major role in the global carbon cycle. Previous studies on the capacity of forests to sequester atmospheric CO2 have mostly focused on carbon uptake, but the roles of carbon turnover time and its spatiotemporal changes remain poorly understood. Here, we used long-term inventory data (1955-2018) from 695 mature forest plots to quantify temporal trends in living vegetation carbon turnover time across tropical, temperate, and cold climate zones, and compared plot data to eight Earth system models (ESMs). Long-term plots consistently showed decreases in living vegetation carbon turnover time, likely driven by increased tree mortality across all major climate zones. Changes in living vegetation carbon turnover time were negatively correlated with CO2 enrichment in both forest plot data and ESM simulations. However, plot-based correlations between living vegetation carbon turnover time and climate drivers such as precipitation and temperature diverged from those of ESM simulations. Our analyses suggest that forest carbon sinks are likely to be constrained by a decrease in living vegetation carbon turnover time, and accurate projections of forest carbon sink dynamics will require an improved representation of tree mortality processes and their sensitivity to climate in ESMs.
- Subject:
- Forestry
- Creator:
- Anderegg, William R.L., Schraub, Marcus, Yu, Kailiang, Gessler, Arthur, Penuelas, Josep, Cailleret, Maxine, Peng, Changhui, Condit, Richard, Ferretti, Marco, Hubbell, Stephen P., Smith, William K., Sardans, Jordi, Levanic, Tom, Zhu, Kai, and Trugman, Anna T.
- Owner:
- KAILIANG YU
- Language:
- English
- Date Uploaded:
- 10/24/2019
- Date Modified:
- 12/09/2021
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/doi:10.7278/S50D-D656-FSP2
-
- Description:
- Data were collected from the free online available International Ionosphere Reference (IRI) database ( https://kauai.ccmc.gsfc.nasa.gov/instantrun/iri) for January 1, 2020. The data were then interpolated from 1km to our desired resolution of 0.1km. This is is profile used to simulate the 3D FDTD models to observe the propagation of power line harmonic radiation through the ionosphere.
- Keyword:
- Ionosphere and Inhomogeneous Ionosphere
- Subject:
- FDTD (mathematics), plasmas (physics) , and ionospheric electron density
- Creator:
- Pedgaonkar, Apoorva
- Owner:
- Based Near Label Tesim:
- Salt Lake City, Utah, United States
- Language:
- English
- Date Uploaded:
- 07/12/2024
- Date Modified:
- 09/06/2024
- Date Created:
- 2020-01-20
- License:
- Public Domain – This data is free of copyright restrictions (e.g. government sponsored data).
- Resource Type:
- Dataset
- Identifier:
- http://doi.org/10.7278/S5d-hpp0-g1wy
-
- Description:
- Dataset for: The Impact of Design Factors on User Behavior in a Virtual Hospital Room to Explore Fall Prevention Strategies
- Keyword:
- hospital room and fall prevention
- Subject:
- Patients' Rooms and Accident Prevention
- Creator:
- Nooshin Seddighi, Peter C. Fino, and Bob Wong
- Owner:
- Madison Golden
- Based Near Label Tesim:
- University of Utah, Utah, United States
- Language:
- English
- Date Uploaded:
- 11/09/2023
- Date Modified:
- 04/10/2024
- Date Created:
- 2022-07-14 to 2022-11-18
- License:
- Other – See README file for more information.
- Resource Type:
- Dataset
- Identifier:
- DOI: 10.7278/S50d-evm5-vh17
-
- Description:
- This dataset summarizes burial counts according to burial type (free, temporary, or perpetual) for the cemeteries of Père-Lachaise, Montmartre, and Montparnasse in Paris. The data covers the period of 1804 to 1840 and was derived from the digitized daily records of burial for the city of Paris, which are currently held in the Archives de Paris. See Registres journaliers d'inhumation https://archives.paris.fr/r/216/cimetieres). These data are organized by the number of each burial type recorded per page of the digitized records.
- Keyword:
- Paris, burial, Montparnasse, and Pere-Lachaise
- Subject:
- Paris, Montparnasse, and Père-Lachaise, Cimetière du
- Creator:
- Alexander, Kaylee P.
- Owner:
- Kaylee Alexander
- Based Near Label Tesim:
- Paris, Île-de-France, France
- Language:
- English
- Date Uploaded:
- 02/11/2023
- Date Modified:
- 06/03/2024
- Date Created:
- 2019-01-01 to 2021-01-01
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50d-d18q-yfzt
-
- Description:
- The Andes Cordillera, which runs the length of South America and rises up to 5,000 m MSL within 200 km of the Pacific coast, dramatically influences the distribution of winter precipitation and snowpack over Chile and Argentina. The study of orographic precipitation processes, particularly along the western slopes of the Andes, is important to improve forecasts of severe flooding and snowpack in a region that depends on snowmelt for water resources. While orographic effects have been investigated on synoptic scales in the Andes, the lack of operational radar coverage and high-elevation, long-term precipitation records have, before the present study, precluded an in-depth investigation into the mesoscale and microphysical processes that affect the distribution of precipitation in the region. This dataset was collected during the Chilean Orographic and Mesoscale Precipitation Study (ChOMPS), which, from May-October 2016, investigated the evolution of precipitation amounts, dropsize distribution, and the vertical profile of radar echoes along an east-west transect that stretched from the Pacific coast to the windward slope of the Andes. The transect, at ~36°S, was made up of a coastal site upstream of the coastal mountain range (Concepción), a central valley site (Chillán), and a mountain site (Las Trancas). Instrumentation along the transect included three vertically pointing Micro-Rain-Radars, two Parsivel Disdrometers, and several meteorological stations. The dataset documents the evolution of Doppler velocity and reflectivity profiles with inland extent during early, middle, and late storm sectors. Additionally, the transect provides a season-long record of the inland evolution of melting layer height as well as the prevalence and structure of shallow non-brightband rain and the characteristics of its inland penetration to the central valley. This dataset, the first of its kind in the Chilean Andes, provides unique insight into mesoscale and orographic precipitation processes that also have applicability to the west coast of the United States and other mountainous regions.
- Subject:
- Meteorology
- Creator:
- Campbell, Leah S., Minder, Justin, and Garreaud, Rene
- Contributor:
- Steenburgh, Jim, Rojas, Yazmina, Viscarra, Also, Montecinos, Aldo, Veloso, Daniel Sebastian, and Salazar, Diego Rivera
- Owner:
- Leahs Campbell
- Based Near Label Tesim:
- Chile, , Chile
- Language:
- English
- Date Uploaded:
- 05/16/2020
- Date Modified:
- 12/09/2021
- Date Created:
- May 15 2016 - October 7 2016
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/doi:10.7278/S50DJXEW0JH3
-
- Description:
- Background: The objective of this study was to evaluate the effect of utilising larger lens cubes on phacoemulsification efficiency and chatter using 3 tips of different sizes and 2 ultrasound (US) approaches. Methods: This was an in vitro laboratory study conducted at the John A. Moran Eye Center Laboratory, University of Utah, Salt Lake City, UT, USA. Porcine lens nuclei were formalin-soaked for 2 hours, then divided into either 2.0 mm or 3.0 mm cubes. 30 degree bent 19 G, 20 G, and 21 G tips were used with a continuous torsional US system; and straight 19 G, 20 G, and 21 G tips were used with a micropulse longitudinal US system. Efficiency and chatter were determined. Results: Mean phacoemulsification removal time was higher with the 3.0 mm lens cube for all US variations and tip sizes. There were statistically significant differences between the 19 G and 21 G tips with micropulse longitudinal US using the 2.0 mm lens cube and the 3.0 mm lens cube, as well as with continuous transversal US using the 2.0 mm lens cube and the 3.0 mm lens cube. There was no significant difference between 19 G and 20 G tips with either lens cube size in either US approach. However, using both US approaches, trends were identical for both lens cube sizes in which the 19 G tips performed better than the 20 G and 21 G tips. Conclusion: Regardless of lens size, the 19 G needle was the most efficient, with the fewest outliers and smallest standard deviations.
- Subject:
- ophthalmology
- Creator:
- Barlow, William R., Bernhisel, Ashlie A., Zaugg, Brian, Olson, Randall J., Ramshekar, Aniket, Heczko, Joshua B., and Pettey, Jeff H.
- Depositor:
- Susan Schulman
- Owner:
- Jeff Pettey
- Based Near Label Tesim:
- Salt Lake City, Utah, United States
- Language:
- English
- Date Uploaded:
- 11/26/2019
- Date Modified:
- 12/09/2021
- Date Created:
- 20180201 - 20180204
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/doi:10.7278/S50D-ZTWP-VF00