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  • Human and Ovine Vitreoretinal Adhesion

    Description:
    While several studies have qualitatively investigated age- and region-dependent adhesion between the vitreous and retina, no studies have directly measured the vitreoretinal strength of adhesion. In this study, we developed a rotational peel device and associated methodology to measure the maximum and steady-state peel forces between the vitreous and the retina. Vitreoretinal adhesion in the equator and posterior pole were measured in human eyes from donors ranging 30 to 79 years of age, and in sheep eyes from premature, neonatal, young lamb, and young adult sheep. In human eyes, maximum peel force in the equator (7.24 ± 4.13 mN) was greater than in the posterior pole (4.08 ± 2.03 mN). This trend was especially evident for younger eyes from donors 30 to 39 years of age. After 60 years of age, there was a significant decrease in the maximum equatorial (4.69 ± 2.52 mN, p = 0.016) and posterior pole adhesion (2.95 ± 1.25 mN, p = 0.037). In immature sheep eyes, maximum adhesion was 7.60 ± 3.06 mN, and did not significantly differ between the equator and posterior pole until young adulthood. At this age, the maximum adhesion in the equator nearly doubled (16.67 ± 7.45 mN) that of the posterior pole, similar to the young adult human eyes. Light microscopy images suggest more disruption of the inner limiting membrane (ILM) in immature sheep eyes compared to adult sheep eyes. Interestingly, in human eyes, ILM disruption was significantly greater in the posterior pole (p < 0.05) and in people over 60 years of age (p < 0.02). These findings supplement the current discussion surrounding age-related posterior vitreous detachment, and the risk factors and physiological progressions associated with this condition. In addition, these data further our understanding of the biomechanical mechanisms of vitreoretinal adhesion, and can be used to develop age- appropriate computational models simulating retinal detachment, hemorrhaging, or retinal trauma. See Creveling CJ, Colter J, Coats B. 2018. Changes in vitreoretinal adhesion with age and region in human and sheep eyes. Frontiers in Bioengineering and Biotechnology 6.  https://doi.org/10.3389/fbioe.2018.00153.
    Keyword:
    ophthalmology, retina, vitreous, adhesion, ocular, human, eye, peel test, and sheep
    Subject:
    Quantitative measurement and Vitreoretinal adhesion
    Creator:
    Coats, Brittany and Creveling, Christopher
    Contributor:
    Colter, Jourdan
    Owner:
    BRIAN MCBRIDE
    Based Near Label Tesim:
    Salt Lake City, Utah, United States
    Language:
    English
    Date Uploaded:
    07/10/2019
    Date Modified:
    06/03/2024
    Date Created:
    Completed 2017-06-01
    License:
    CC BY – Allows others to use and share your data, even commercially, with attribution.
    Resource Type:
    Image, Dataset, and Video
    Identifier:
    https://doi.org/10.7278/S5BK19H3

  • Dataset for: Survey of Anime Convention Attendance in Response to COVID-19

    Description:
    This dataset encompasses the valid, completed, and qualitative data collected during the 2021 “Survey of Anime Convention Attendance in Response to Covid-19.” This survey was distributed online through social media platforms, community spaces, and industry listservs/resources in order to reach organizers, attendees, and fans of anime conventions (i.e., “cons”). The survey was intended to discover how those who attend anime conventions (i.e., "con-goers") have been experiencing changes in the anime convention scene during the COVID-19 pandemic, particularly in 2020-2021. Traditionally, anime cons and con-related activities such as cosplay (dressing up as a favorite character) are held in person. However, in 2020-2021, most cons have been cancelled or moved online; this is the first time in over 40 years, in the US and worldwide, that the anime convention scene has been so quiet. With this survey, investigators sought to capture firsthand impressions of this unprecedented moment, learning how con-goers were experiencing these changes and whether they had safety or other concerns about anime cons returning in late 2021 and early 2022.
    Keyword:
    anime, COVID-19, consumer studies, anime conventions, popular culture, pandemic, consumers, conventions, and fans
    Subject:
    Popular Culture
    Creator:
    Alberto, Maria and Tringali, Billy
    Owner:
    Language:
    English
    Date Uploaded:
    09/16/2021
    Date Modified:
    06/03/2024
    Date Created:
    2021-05-01 to 2021-09-01
    License:
    CC BY – Allows others to use and share your data, even commercially, with attribution.
    Resource Type:
    Dataset
    Identifier:
    https://doi.org/10.7278/S50D-8FF8-NT67

  • HPV Vaccine Survey Responses

    Description:
    Background: To assess the demographic and attitudinal factors associated with HPV vaccine initiation and completion among 18–26 year old women in Utah. Method: Between January 2013 and December 2013, we surveyed 325 women from the University of Utah Community Clinics about their HPV vaccine related beliefs and behaviors. Odds ratios (ORs) were estimated from logistic regression models to identify variables related to HPV vaccine initiation and series completion. Results: Of the 325 participants, 204 (62.8 %) had initiated the vaccine and 159 (48.9 %) had completed the 3-dose series. The variables associated with HPV vaccine initiation were lower age (OR = 1.18 per year); being unmarried (OR = 3.62); not practicing organized religion (OR = 2.40); knowing how HPV spreads (OR = 6.29); knowing the connection between HPV and cervical cancer (OR = 3.90); a belief in the importance of preventive vaccination (OR = 2.45 per scale unit); strength of doctor recommendation (OR = 1.86 per scale unit); and whether a doctor’s recommendation was influential (OR = 1.70 per scale unit). These variables were also significantly associated with HPV vaccine completion. Conclusion: The implications of these findings may help inform policies and interventions focused on increasing HPV vaccination rates among young women. For example, without this information, programs might focus on HPV awareness; however, the results of this study illustrate that awareness is already high (near saturation) in target populations and other factors, such as strong and consistent physician recommendations, are more pivotal in increasing likelihood of vaccination. Additionally, our findings indicate the need for discussions of risk assessment be tailored to the young adult population.
    Keyword:
    immunization, Gardasil, vaccination, human papillomavirus, HPV, completion, intention, and vaccine series
    Subject:
    Papillomavirus Vaccines and Patient Compliance
    Creator:
    Kepka, Deanna and Wilson, Andrew
    Contributor:
    University of Utah Primary Care Research Network, Huntsman Cancer Institute, and Huntsman Cancer Foundation
    Owner:
    BRIAN MCBRIDE
    Based Near Label Tesim:
    Utah, Utah, United States and Utah, Utah, United States
    Language:
    English
    Date Uploaded:
    07/10/2019
    Date Modified:
    04/17/2024
    Date Created:
    2013-01-01 to 2013-12-31
    License:
    CC BY NC - Allows others to use and share your data non-commercially and with attribution.
    Resource Type:
    Dataset
    Identifier:
    https://doi.org/10.7278/S53B5X9S

  • Dataset for: Impact of a Consumer Health Information Specialization (CHIS) Sponsorship Program on Ability of Public Library Staff to Provide Consumer Health Information

    Description:
    Objective: In 2018, the Network of the National Libraries of Medicine (NNLM) launched a national sponsorship program to support U.S. public library staff in completing the Medical Library Association’s (MLA) Consumer Health Information Specialization (CHIS). The primary objective of this research project was to determine if completion of the sponsored specialization was successful in improving public library staff ability to provide consumer health information and whether it resulted in new services, programming, or outreach activities at public libraries. Secondary objectives of this research were to determine motivation for and benefits of the specialization and to determine the impact on sponsorship on obtaining and continuing the specialization. Methods: To evaluate the sponsorship program, we developed and administered a 16-question online survey via REDCap in August 2019 to 224 public library staff that were sponsored during the first year of the program. We measured confidence and competence in providing consumer health information using questions aligned with the eight Core Competencies for Providing Consumer Health Information Services [1]. Additionally, the survey included questions about new consumer health information activities at public libraries, public library staff motivation to obtain the specialization, and whether it led to immediate career gains. To determine the overall value of the NNLM sponsorship, we measured whether funding made it more likely for participants to complete or continue the specialization. Results: Overall, 136 participants (61%) responded to the survey. Our findings indicated that the program was a success: over 80% of participants reported an increase in core consumer health competencies, with a statistically significant improvement in mean competency scores after completing the specialization. Ninety percent of participants have continued their engagement with NNLM, and over half offered new health information programs and services at their public library. All respondents indicated that completing the specialization met their expectations, but few reported immediate career gains. While over half of participants planned to renew the specialization or obtain the more advanced, Level II specialization, 72% indicated they would not continue without the NNLM sponsorship. Conclusion: Findings indicate that NNLM sponsorship of the CHIS specialization was successful in increasing the ability of public library staff to provide health information to their community. and This dataset represents the de-identified raw results of a 16-question, online survey (via REDCap) collected in August 2019 to 224 public library staff who were sponsored for a Consumer Health Information Specialization (CHIS). The purpose of the study was to determine whether the sponsorship program had an impact on public library staff to provide consumer health information.
    Keyword:
    public libraries, CHIS, medical libraries , library science, information literacy, consumer health information specialization , and REDCap
    Subject:
    Interprofessional Relations, Information Services, Professional Competence, Librarians, Medical libraries, Consumer Health Information, and Humans
    Creator:
    Lake, Erica, Wolfe, Susan M, Knapp, Molly , Spatz, Michele, and Kiscaden, Elizabeth
    Owner:
    Molly Knapp
    Based Near Label Tesim:
    United States, , United States
    Language:
    English
    Date Uploaded:
    11/12/2020
    Date Modified:
    10/25/2024
    Date Created:
    2019-08-01 to 2019-08-31
    License:
    CC BY NC - Allows others to use and share your data non-commercially and with attribution.
    Resource Type:
    Dataset
    Identifier:
    https://doi.org/10.7278/S50D1DAY2QQQ