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- Description:
- We discuss a new set of ~ 500 numerical n-body calculations designed to constrain the masses and bulk densities of Styx, Nix, Kerberos, and Hydra. Comparisons of different techniques for deriving the semimajor axis and eccentricity of the four satellites favor methods relying on the theory of Lee & Peale (2006), where satellite orbits are derived in the context of the restricted three body problem (Pluto, Charon, and one massless satellite). In each simulation, we adopt the nominal satellite masses derived in Kenyon & Bromley (2019b), multiply the mass of at least one satellite by a numerical factor f >= 1, and establish whether the system ejects at least one satellite on a time scale <= 4.5~Gyr. When the total system mass is large (f >> 1), ejections of Kerberos are more common. Systems with lower satellite masses (f ~ 1) usually eject Styx. In these calculations, Styx often signals an ejection by moving to higher orbital inclination long before ejection; Kerberos rarely signals in a useful way. The n-body results suggest that Styx and Kerberos are more likely to have bulk densities comparable with water ice, rho_SK <= 2 g/cm^3, than with rock. A strong upper limit on the total system mass, M_SNKH <= 9.5 x 10^19 g, also places robust constraints on the average bulk density of the four satellites, rho_SNKH <= 1.4 g/cm^3. These limits support models where the satellites grow out of icy material ejected during a major impact on Pluto or Charon.
- Keyword:
- Nix, dynamic evolution, satellites , Hydra, Styx, Charon, model, Pluto, planets, and Kerberos
- Subject:
- Astrophysics
- Creator:
- Kenyon, Scott and Bromley, Benjamin
- Owner:
- BENJAMIN BROMLEY
- Based Near Label Tesim:
- United States, , United States
- Date Uploaded:
- 04/01/2022
- Date Modified:
- 12/06/2023
- Date Created:
- 2019-05-15 to 2022-03-25
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50d-5g6f-yfc5
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- Description:
- Current treatments for methicillin-resistant Staphylococcus aureus (MRSA) infections require intravenously delivered vancomycin; however, systemically delivered vancomycin has its problems. To determine the feasibility and safety of locally delivering vancomycin hydrochloride (~25 mg/Kg) to the medullary canal of long bones, we conducted a pharmacokinetics study using a rat tibia model. We found that administering the vancomycin intraosseously resulted in very low concentrations of vancomycin in the blood plasma and the muscle surrounding the tibia, reducing the risk for systemic toxicity, which is often seen with traditional intravenous administration of vancomycin. Additionally, we were able to inhibit the development of osteomyelitis in the tibia if the treatment was administered locally at the same time as a bacterial inoculum (i.e., Log10 7.82 CFU/mL or 6.62x107 CFU/mL), when compared to an untreated group. These findings suggest that local intramedullary vancomycin delivery can achieve sufficiently high local concentrations to prevent development of osteomyelitis while minimizing systemic toxicity.
- Keyword:
- pharmacokinetics, tibia, infections, systematic toxicity, bone, antibiotics, rat, osteomyelitis, and vancomycin
- Subject:
- Infectious Diseases
- Creator:
- Loc-Carrillo, Catherine
- Contributor:
- Wu, Sijia, Fernandez, Sheena, Burr, Michael, Fredricksen, Hunter, Canden, Ahranee, Hoerger, Kelly, Churchill, John, Wang, Caroline, and Agarwal, Jay
- Owner:
- BRIAN MCBRIDE
- Based Near Label Tesim:
- Salt Lake City, Utah, United States
- Language:
- English
- Date Uploaded:
- 07/10/2019
- Date Modified:
- 04/16/2024
- Date Created:
- 2013-05-01 to 2015-01-30
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S5W0942B
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- Description:
- Datasets include interviews and observations of healthcare staff in 25 long-term care facilities across 7 states and two data collection visits to understand frequency, type, and reason (i.e., types of care activities provided during an interaction) for staff-resident interactions in 2019 and 2020. Staff-resident interactions were studied to examine potential for multidrug-resistant organism (MDRO) transmission within long-term care settings.
- Keyword:
- transmission, infection prevention, multidrug-resistant organism (MDRO), long-term care facility, care delivery patterns, and nursing home
- Subject:
- infection prevention, nursing homes, and healthcare-associated infection
- Creator:
- University of Utah Epicenter
- Owner:
- Date Uploaded:
- 04/15/2024
- Date Modified:
- 04/16/2024
- Date Created:
- 2019-01-01 to 2020-06-01
- License:
- Public Domain – This data is free of copyright restrictions (e.g. government sponsored data).
-
Data for: Restitution Characteristics of His Bundle and Working Myocardium in Isolated Rabbit Hearts
- Description:
- The Purkinje system (PS) and the His bundle have been recently implicated as an important driver of the rapid activation rate after 1-2 minutes of ventricular fibrillation (VF). It is unknown whether activations during VF propagate through the His-Purkinje system to other portions of the the working myocardium (WM). Little is known about restitution characteristic differences between the His bundle and working myocardium at short cycle lengths. In this study, rabbit hearts (n=9) were isolated, Langendorff- perfused, and electromechanically uncoupled with blebbistatin (10 μM). Pacing pulses were delivered directly to the His bundle. By using standard glass microelectrodes, action potentials duration (APD) from the His bundle and WM were obtained simultaneously over a wide range of stimulation cycle lengths (CL). The global F-test indicated that the two restitution curves of the His bundle and the WM are statistically significantly different (P<0.05). Also, the APD of the His bundle was significantly shorter than that of WM throughout the whole pacing course (P<0.001). The CL at which alternans developed in the His bundle vs. the WM were shorter for the His bundle (134.2±13.1ms vs. 148.3±13.3ms, P<0.01) and 2:1 block developed at a shorter CL in the His bundle than in WM (130.0±10.0 vs. 145.6±14.2ms, P<0.01). The His bundle APD was significantly shorter than that of WM under both slow and rapid pacing rates, which suggest that there may be an excitable gap during VF and that the His bundle may conduct wavefronts from one bundle branch to the other at short cycle lengths and during VF.
- Keyword:
- ventricular fibrillation, action potential duration, cardiology, working myocardium, rabbit, restitution curve, alternans, His bundle, and microelectrode
- Subject:
- ventricular fibrillation, cardiology, and myocardium
- Creator:
- Huang, Shangwei, Panitchob, Nuttanont, Hu, Nan, Ranjan, Ravi, Huang, Liqun, and Dosdall, Derek
- Owner:
- BRIAN MCBRIDE
- Based Near Label Tesim:
- Salt Lake City, Utah, United States
- Language:
- English
- Date Uploaded:
- 07/10/2019
- Date Modified:
- 04/18/2024
- Date Created:
- 2016-03-21 to 2016-05-25
- License:
- CCO – As the data author, you are choosing to place your data into the public domain.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50R9MJX
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- Description:
- This dataset encompasses the valid, completed, and qualitative data collected during the 2021 “Survey of Anime Convention Attendance in Response to Covid-19.” This survey was distributed online through social media platforms, community spaces, and industry listservs/resources in order to reach organizers, attendees, and fans of anime conventions (i.e., “cons”). The survey was intended to discover how those who attend anime conventions (i.e., "con-goers") have been experiencing changes in the anime convention scene during the COVID-19 pandemic, particularly in 2020-2021. Traditionally, anime cons and con-related activities such as cosplay (dressing up as a favorite character) are held in person. However, in 2020-2021, most cons have been cancelled or moved online; this is the first time in over 40 years, in the US and worldwide, that the anime convention scene has been so quiet. With this survey, investigators sought to capture firsthand impressions of this unprecedented moment, learning how con-goers were experiencing these changes and whether they had safety or other concerns about anime cons returning in late 2021 and early 2022.
- Keyword:
- anime, COVID-19, consumer studies, anime conventions, popular culture, pandemic, consumers, conventions, and fans
- Subject:
- Popular Culture
- Creator:
- Alberto, Maria and Tringali, Billy
- Owner:
- Language:
- English
- Date Uploaded:
- 09/16/2021
- Date Modified:
- 06/03/2024
- Date Created:
- 2021-05-01 to 2021-09-01
- License:
- CC BY – Allows others to use and share your data, even commercially, with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50D-8FF8-NT67
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- Description:
- This dataset is a custom Kraken2 formatted database for the identification of Fungi from shotgun metagenomic data. Kraken2 is a k-mer based read classifier (Wood et al. 2019; https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1891-0). The dataset was built with the default k-mer length (k=35) from all publicly available fungal genomes at JGI Mycocosm ( https://mycocosm.jgi.doe.gov/mycocosm/home), and all archaea, bacteria, viral, plasmid, human, fungi, plant, and protozoa genomes, as well as the UniVec Core and nt reference database at NCBI ( https://www.ncbi.nlm.nih.gov/). The reference genomes and sequences were downloaded from JGI and NCBI in March 2020.
- Keyword:
- protozoa, Kraken2 database, plant, bacteria, genomes, fungi, human, archaea, plasmid, and virus
- Subject:
- Mycology and Genomics
- Creator:
- Dentinger, Bryn T. M.
- Owner:
- Bryn Dentinger
- Language:
- English
- Date Uploaded:
- 06/08/2022
- Date Modified:
- 06/03/2024
- Date Created:
- 2020-03-29
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Software or Program Code and Dataset
- Identifier:
- https://doi.org/10.7278/S50d-154b-fppf
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- Description:
- This study aims to quantify rare earth element enrichment within coal and coal-adjacent strata in the Uinta Region of Utah and western Colorado. Rare earth elements are a subset of critical minerals used for renewable energy technology in the transition toward carbon-neutral energy. This data contains samples from seven active mines and seven stratigraphically complete cores within the Uinta Region, geochemically evaluated via portable X-ray fluorescence (n=3,113) and inductively coupled plasma-mass spectrometry (n=143) elemental abundance methods. Historical evaluations of geochemical data on Uinta Region coal and coal-adjacent data are sparse, emphasizing the statistical significance of this study’s analyses. These results support the utilization of active mines and coal processing waste piles for the future of domestic rare earth element extraction, offering economic and environmental solutions to pressing global demands.
- Keyword:
- Mesaverde Group, Cretaceous, coal, critical minerals, energy transition, Blackhawk Formation, Uinta Region, and rare earth elements
- Subject:
- stratigraphy, geochemistry, coal resources, sedimentology, and economic geology
- Creator:
- Birgenheier, Lauren, Coe, Haley, Gall, Ryan, Fernandez, Diego, Giebel, Andrew, Vanden Berg, Michael D., and Free, Michael
- Contributor:
- Hamidat, Amin and Starkie, Erin
- Owner:
- Based Near Label Tesim:
- Salt Lake City, Utah, United States, Uinta Basin, Utah, United States, and Piceance Creek Basin, Colorado, United States
- Language:
- English
- Date Uploaded:
- 12/14/2023
- Date Modified:
- 12/19/2023
- Date Created:
- 2022-05-23 to 2023-03-01
- License:
- Public Domain – This data is free of copyright restrictions (e.g. government sponsored data).
- Resource Type:
- Dataset
- Identifier:
- www.doi.org/10.7278/S50d-5ny1-1wc1
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- Description:
- Environmental noise may affect hearing and a variety of non-auditory disease processes. There is some evidence that, like other environmental hazards, noise may be differentially distributed across communities based on socioeconomic status. We aimed to a) predict daytime noise pollution levels and b) assess disparities in daytime noise exposure in Chicago, Illinois. We measured 5-minute daytime noise levels (Leq, 5-min) at 75 randomly selected sites in Chicago in March 2019. Geographically based variables thought to be associated with noise were obtained and used to fit a noise land-use regression model to estimate the daytime environmental noise level at the centroid of the census blocks. Demographic and socioeconomic data were obtained from the City of Chicago for the 77 community areas, and associations with daytime noise levels were assessed using spatial autoregressive models. Mean sampled noise level (Leq, 5-min) was 60.6 dBA. The adjusted R2 and root mean square error of the noise land use regression model and the validation model were 0.60 and 4.67 dBA and 0.51 and 5.90 dBA, respectively. Nearly 75% of city blocks and 85% of city communities have predicted daytime noise level higher than 55 dBA. Of the socioeconomic variables explored, only community per capita income was associated with mean community predicted noise levels and was highest for communities with incomes in the 2nd quartile. Both the noise measurements and land-use regression modeling demonstrate that Chicago has levels of environmental noise likely contributing to the total burden of environmental stressors. Noise is not uniformly distributed across Chicago; it is associated with proximity to roads and public transportation and is higher among communities with mid-to-low incomes per capita, which highlights how socially and economically disadvantaged communities may be disproportionately impacted by this environmental exposure.
- Keyword:
- noise, land use regression, health disparities, geospatial data, and environmental exposure
- Subject:
- Environmental Sciences
- Creator:
- Conroy, Lorraine M., Huang, Yu-Kai, Mitchell, Uchechi A., and Jones, Rachael M.
- Owner:
- Rachael Jones
- Based Near Label Tesim:
- Chicago, Illinois, United States
- Language:
- English
- Date Uploaded:
- 05/19/2021
- Date Modified:
- 05/01/2024
- Date Created:
- 2019-03-01 to 2019-03-31
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50D-SPT1-FNHH
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- Description:
- The dataset was collected in the process of carrying out a research on the effects of photochemical aging and interactions with secondary organic aerosols on cellular toxicity of combustion particles between the year 2021 to 2022
- Keyword:
- combustion particles, photochemical aging, and secondary organic aerosols
- Subject:
- combustion, combustion products, photochemical reactions, and aerosols
- Creator:
- Reuben, Attah, Kelly, Kerry, and Kaur, Kamaljeet
- Owner:
- Reuben Attah
- Based Near Label Tesim:
- University of Utah, Utah, United States
- Language:
- English
- Date Uploaded:
- 02/09/2023
- Date Modified:
- 06/03/2024
- Date Created:
- 2021-06-01 to 2022-12-31
- License:
- CC BY – Allows others to use and share your data, even commercially, with attribution.
- Resource Type:
- Dataset
- Identifier:
- https://doi.org/10.7278/S50d-2a2h-jeaa
-
- Description:
- This study investigates the internal facies architecture of a river-dominated delta deposit using outcrops of the Cretaceous Panther Tongue of the Star Point Sandstone in central Utah, U.S.A. A series of photorealistic virtual outcrop models (VOM) were created from ~13 linear-km of outcrop. These VOMs, alongside field observations, were used to identify and map facies and facies associations over the ~25 m-thick stratigraphic interval. A new workflow for querying VOMs as outcrop analogs for subsurface reservoir analogs was developed, using a database of measurements (Panther Tongue - outcrop analog - metric database) was constructed using 60 digital sections that were measured within the VOMs at 152 m (~500 ft) spacing. This database characterizes a total of 508 sandstone beds by their thickness, length, and dip, from which the average thickness (0.78 m), bed length (330 m), and bed dip (2˚ towards the south) were calculated. Thinning rates were also calculated in both depositional strike and depositional dip directions (1.37x10-2 and 1.01x10-2 respectively). The workflow established in this study is applicable to other sedimentary outcrops and environments, thus demonstrating that VOMs can be used as a basis for quantitative database development and reservoir modeling inputs.
- Keyword:
- shallow marine sedimentology, outcrop metrics, and Virtual outcrop models of ancient river-dominated delta system
- Subject:
- Cretaceous Period, Outcrops, and Deltas
- Creator:
- Morris, Emma, Johnson, Cari, and Atlas, Claire
- Owner:
- Emma Morris
- Based Near Label Tesim:
- Helper, Utah, United States
- Language:
- English
- Date Uploaded:
- 04/07/2023
- Date Modified:
- 06/03/2024
- Date Created:
- 2020-01-01 to 2022-05-31
- License:
- CC BY NC - Allows others to use and share your data non-commercially and with attribution.
- Resource Type:
- Other
- Identifier:
- https://doi.org/10.7278/S50d-njws-r7tz