The objective of using the wireless sensors was to improve understanding of the heterogeneity of healthcare worker (HCW) contact with patients and the physical environment in patients’ rooms. The framework and design were based on contact networks with a) nodes defined by HCW’s, rooms, and items in the room and b) edges defined by HCW’s in the room, near the bed, and touching items. Nodes had characteristics of HCW role and room number. Edges had characteristics of day, start time, and duration. Thus, patterns and heterogeneity could be understood within contexts of time, space, roles, and patient characteristics. At the University of Utah Hospital Cardiovascular ICU (CVICU), a 20-bed unit, we collected data for 54 days. HCW contact with patients was measured using wireless sensors to capture time spent in patient rooms as well as time spent near the patient bed. HCW contact with the physical environment was measured using wireless sensors on the following items in patient rooms: door, sink, toilet, over-bed table, keyboard, vital signs monitor touchscreen, and cart. HCW’s clipped a sensor to their clothing or lanyard.